AltTox Digest
October 2009

ZEBET 20^th Anniversary

The German alternatives center, formally known as the National Centre for Documentation and Evaluation of Alternatives to Animal Experiments but better known by its German acronym "ZEBET," celebrated its 20^th anniversary with a symposium held on October 26-27 at the Federal Institute for Risk Assessment, in Berlin. Among national alternatives centers, ZEBET has an unparalleled track record of achievement in developing and/or validating non-animal testing methods. ZEBET's accomplishments in this regard include methods for skin irritation, -corrosion and -penetration, phototoxicity, acute toxicity, and embryotoxicity, among others.

ZEBET is also active in other areas. It has established the AnimAlt-ZEBET database, an important search tool for alternative methods. (The English language version is available free of charge at http://www.bfr.bund.de/cd/1508.) It operates advisory services on animal experimentation for public authorities, ministries, and scientists.

Dr. Horst Spielmann was the director of ZEBET from its start in 1989 through 2007. AltTox Forum users know Dr. Spielmann as a moderator of the Toxicity Endpoints & Tests Forum and frequent contributor to the various AltTox Forums. Other long-term ZEBET staff include Drs. Manfred Liebsch, Barbara Grune, and Andrea Seiler. Congratulations to the full staff of ZEBET for 20 years of accomplishment. A video and brochure commemorating ZEBET's work are available for viewing at http://www.bfr.bund.de/cd/30993 and http://www.bfr.bund.de/cd/30995, respectively.

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Forum Postings

Some of the recent posts on the AltTox Forums include the following:

Toxicity Endpoints & Tests forum

• ECVAM discourages the LOW VOLUME EYE TEST (LVET)
• ECVAM statement on CYTOTOXICITY-CELL based assays for eye irritation

Emerging Technologies forum

• Quality control in microarray assessment of gene expression in human airway epit
• Using Toxicogenomic Data in U.S. EPA Human Health Risk Assessment
• New look for the OECD (Q)SAR Application Toolbox website

Programs & Policies forum

• US EPA's Endocrine Disrupter Screening Program
• Korean developments
• ECVAM needs excellent scientists for its new Scientific Advisory Structure
• ICATM

Overarching Challenges & Opportunities forum

• No Recent Posts

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The AltTox.org Management Team and Editorial Board strive to give readers the most up-to-date summary information related to non-animal methods of toxicity testing. Check out our latest material:

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Upcoming Events

Here are some of the many upcoming events listed on AltTox that may be of interest to the AltTox community:

• Simcyp In Vitro-In Vivo Extrapolation Workshop, November 2-6, 2009, La Jolla, California, US
• KoCVAM International Symposium and 6^th Congress of KSAAE, November 3, 2009, Seoul, Korea
• Implementation of the U.S. National Research Council Report on Toxicity Testing in the 21^st Century: Can We Make the Business Case for Alternatives?, November 5, 2009, Chicago, Illinois, US
• EPAA Annual Conference 2009, November 6, 2009, Brussels, Belgium
• NC3Rs Workshop: Novel approaches to safety assessment, November 11-12, 2009, London, UK
• CAAT Chemical Information Day, November 11, 2009, Baltimore, Maryland, US
• Japanese Society for Alternatives to Animal Experiments (JSAAE) 22^nd Annual Meeting, November 13-15, 2009, Osaka, Japan
• 11^th Cefic LRI Annual workshop, November 19, 2009, Brussels, Belgium
• FRAME 40^th Anniversary Event/Drug Discovery and Development in the 21^st Century, November 19, 2009, London, UK
• BELTOX/INVITROM Meeting: Liver toxicity - From In Vitro to Man, November 25, 2009, Edegem, Belgium
• In Vitro Testing Industrial Platform's (IVTIP) Meeting: Toxicology in the 21^st Century, November 26, 2009, Antwerp, Belgium

More Events >>

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