AltTox Digest
June 2009

Three Rs Anniversaries

This year marks the 50^th anniversary of the publication of William Russell and Rex Burch's landmark book, The Principles of Humane Experimental Technique, which elaborated the Three Rs approach of replacing, reducing, and refining the use of animals in biomedical experimentation.

The anniversary will be celebrated at the upcoming World Congress on Alternatives and Animal Use in the Life Sciences, to be held in Rome later this summer. For Russell, who died in 2006, the World Congress on Alternatives is a fitting venue for this tribute. Ten years ago, at the third World Congress, Russell delivered an entertaining lecture before an audience of several hundred conferees—arguably the highlight of his involvement with the scientists, animal protectionists, and others who had come to form the Three Rs community.

By happy coincidence, 2009 also marks another important anniversary in Three Rs history—the 40^th year of the founding of FRAME (Fund for the Replacement of Animals in Medical Experiments). The British charity has done much over the years to promote alternative methods, including publishing the Three Rs community's flagship journal ATLA (Alternatives to Laboratory Animals). FRAME recently held a workshop in Notthingham, England, celebrating both anniversaries. During the workshop, two important announcements were made: FRAME has published an abridged version of The Principles, which has long been out of print, and the University of Nottingham will house and preserve Russell's voluminous papers and books.

New Deadlines for the 7^th World Congress

The deadline for early bird registration at the 7^th World Congress on Alternatives & Animal Use in the Life Sciences has been moved back to July 20. The deadline to register online is August 18, and can be done here. After this date, it will only be possible to register on site.

Thank You to our Sponsors!

Forum Postings

Some of the recent posts on the AltTox forums include the following:

Toxicity Endpoints & Tests forum

• Integration of genotoxicity in vivo testing into repeated dose toxicity testing
• Pyrogenicity Survey-Respondents sought

Emerging Technologies forum

• New look for the OECD (Q)SAR Application Toolbox website
• On-line seminars on Computational Toxicology

Programs & Policies forum

• EFSA's Scientific Committee promotes alternatives to animal testing
• WC7 Scientific Programme now online

Overarching Challenges & Opportunities forum

• New commentary on Toxicology in the 21^st Century
• 'Beyond animal research' essay competition

Be sure to visit the forums, respond to previous postings, or start a new message thread.

Enter Forums >>

New and Updated Information

The AltTox.org Management Team and Editorial Board strive to give readers the most up-to-date summary information related to non-animal methods of toxicity testing. Check out our latest material:

In the Spotlight

• Alternatives to Animal Testing Recommendations from the European Food Safety Authority

The Way Forward

• Developmental Toxicity Testing in the 21^st Century: An Opportunity to Take a New Pathway by Ed Carney

Toxicity Testing Resource Center

• Informational Resources
• Meetings & Events
• Databases
• Journals
• Other Literature/Websites
• Testing Supplies, Cells, Tissues, Software

Upcoming Events

Here are some of the many upcoming events listed on AltTox that may be of interest to the AltTox community:

• CAAT Information Day on the 7^th Amendment of the EU Cosmetics Directive, July 8, 2009, Baltimore, Maryland, US
• International Society for Stem Cell Research (ISSCR) 7^th Annual Meeting, July 8-11, 2009, Barcelona, Spain
• American Contact Dermatitis Society State-of-the-Art Meeting, July 9-11, 2009, Hershey, Pennsylvania, US
• BIOCOMP'09 - 2009 International Conference on Bioinformatics & Computational Biology, July 13-16, 2009, Las Vegas, Nevada, US
• Bioinformatics Platform (BIP) Applied Computational Genomics Course, July 14-20, 2009, Calgary, Alberta, Canada
• Reduced Animal Testing, July 23-24, 2009, Zurich, Switzerland
• NTP Board of Scientific Counselors Meeting, July 23-24, 2009, Research Triangle Park, North Carolina, US
• Predictive ADME & Toxicology Workshop, July 27-31, 2009, Oxford, UK

More Events >>

User Participation

We welcome your participation in the AltTox forums, as well as your comments and suggestions, which can be submitted by using the online Website Feedback survey, or by e-mailing info@alttox.org. Please submit your suggestions for the Informational Resources or Events section to info@alttox.org.

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